Investor Presentation Β· 2026
Three Ventures
Building Tomorrow's Health & Safety Brands
GLP-1 Meal App
Healthspan100
ThePrimeYears
Ashish Khera Β· Founder & CEO, Scientific Animations
Portfolio Overview
Three Bets, One Thesis
Health & safety markets underserved by incumbents β addressable through AI-powered, content-first brands with minimal human overhead.
GLP-1 Meal Planner
Injection-cycle-aware meal planning for 15β20M Americans on Ozempic, Wegovy & Mounjaro. Four pillars: nausea management, protein preservation, cycle intelligence, and food noise reset.
Healthspan100
Longevity science media brand. SA's 20yr medical animation IP β viral content engine.
ThePrimeYears
Medication Management App for caregivers + elderly patients managing complex regimens. Newsletter builds audience, app monetizes.
Unfair Advantage
Why Ashish Khera?
20+ years turning complex medical science into visual stories β now applied to three high-growth verticals.
20yr Medical Animation IP
Scientific Animations: Pfizer, J&J, Abbott, Medtronic. Deep health/biotech credibility.
AI-Powered Operations
Steve (OpenClaw agent) runs 90%+ of daily operations. Sub-agents for coding, QC, content.
Visual Storytelling
Complex science β accessible visuals. The exact skill set these brands need.
Cross-Venture Synergy
GLP-1 research feeds Healthspan100 content. SA IP powers all three brands' visuals.
GLP-1 Meal Planner Β· The Problem
Four Pillars No App Has Solved β Until Now
"The food noise stopped β but nobody told me what to eat instead. I'm on 1,200 calories and losing muscle."
β r/Semaglutide user, 2025
Four Interlocking Problems
1. Nausea: GI distress peaks Days 1β2 post-injection. 21.5% of users suffer β the #1 quit reason.
2. Muscle Loss: 25β40% of lost weight is lean mass without protein guidance (semaglutide 40%, tirzepatide 25%).
3. No Cycle Guidance: Drug levels swing 2.7β4Γ weekly β zero apps adapt meals to pharmacokinetic reality.
4. Food Noise Reset (NEW): GLP-1s quiet the brain's mesolimbic reward circuitry β a once-in-a-lifetime neurological window to completely rebuild your relationship with food and habits. No app teaches this.
GLP-1 Β· Market Opportunity
$1.44B SAM in a $66.6B Drug Market
Why Now?
π GLP-1 prescriptions surging
$8.2B (2025) β $66.6B (2035). CAGR 23.3%
π Oral GLP-1 approved Dec 2025
Expands TAM beyond injection users
π₯ No purpose-built solution
Noom, WW, Calibrate: none have injection-cycle awareness
β° 12β18 month window
Before well-funded incumbents copy this approach
GLP-1 Β· Market Strategy
Three Markets. One Sequence. Crystal Clear.
D2C first. B2B/HIPAA next. Pharma never. Each unlocks on the foundation of the previous.
15β20M active GLP-1 users, mostly self-managing. No HIPAA required β self-reported data is consumer health info, not PHI. Prove product here. Build dataset here.
12β18
Obesity medicine clinics, telehealth operators, employer wellness. HIPAA-from-day-one unlocks these conversations months earlier. Provider referral = near-zero CAC.
FDA clearance as medical device. Clinical trials. Regulatory apparatus. Novo & Lilly build their own β different customer, different model.
GLP-1 Β· Our Solution
The Only Injection-Cycle-Aware Meal Planner
Meal plans that automatically adapt to where you are in your weekly GLP-1 injection cycle.
SOOTHE
SOOTHE
NOURISH
NOURISH
BUILD
BUILD
MAINTAIN
Injection
Protein Optimizer
Running daily counter. 1.3g/kg target. Gap alerts at 4PM.
Injection Diary
3-tap daily logging: dose β nausea β meals. Builds proprietary dataset.
Stealth Personalization
6 psychographic profiles. Invisible tone/content adaptation.
GLP-1 Β· Our Moat
Multi-Layer Moat β Four Compounding Layers
Not one moat. Four layers that compound daily and become unreplicable together after 18 months.
50K users + 4 weeks = model better than generic RD advice. 100K users = pharma-grade real-world evidence dataset.
Continuous harvest of 7 subreddits via Apify ($4/mo). NLP classification by drug Γ dose Γ week Γ food Γ outcome. Pattern extraction before our own user base is large enough to detect them independently.
Daily PubMed/bioRxiv harvest β LLM plain-language TLDRs + quality ratings (π’ RCT Β· π‘ Observational Β· π΄ Preliminary). User-submitted studies with community upvoting. Makes us the trusted source of truth GLP-1 users check daily.
Branded shareable progress graphics for Instagram/TikTok. Creator program for power users. "7-Day Nausea-Free Challenge" mechanics. Every shared post drives organic acquisition and community knowledge into the dataset.
| Capability | Us | Pep | Noom GLP-1 | Calibrate |
|---|---|---|---|---|
| Injection-cycle meal planning | β Core | β Tracking only | β | β |
| Clinical Intelligence Engine | β Daily harvest | β | β | β |
| Mood tracking + real-world data | β | β | Partial | β |
| 6 psychological profiles (stealth) | β | β | Basic | β |
GLP-1 Β· Clinical Intelligence Engine
Making Us the Trusted Source of Truth for GLP-1 Users
When a user opens the app to check "any new GLP-1 research today?" β we've won. The app becomes a source they trust, not just a tool they use.
The Pipeline
GLP-1 Β· Mental Health Layer
Real-World Data vs. Clinical Trials β The Divergence Opportunity
Clinical trials exclude patients with depression, anxiety, ADHD. Real-world users are messy. Our data will tell a different story β and that divergence is the gold mine.
Meta-analysis of 91 trials, 107,910 patients: No increased risk of suicidal ideation. FDA requested removal of psychiatric warnings from GLP-1 labels.
Among 2M+ pharmacovigilance reports, semaglutide shows signals for anxiety (aROR 1.26), depressed mood (aROR 1.70), suicidality (aROR 1.45). Trial patients β real patients.
Daily Mood Check-in Design
GLP-1 Β· Business Model & Projections
Path to $1.2M ARR by Month 24
Revenue Model β 4 Tiers
Blended ARPU: $12.50/mo
CAC: β€$25 (organic) Β· LTV:CAC 6:1
Break-even: ~2 months per subscriber
Opex Phase 1: ~$700β$900/mo tools + infra
5-Year ARR Projections
π» Bear
Y3 ARR
π Base
Y3 ARR
π Bull
Y3 ARR
GLP-1 Β· Operations
Near-Autonomous: 1 Hour/Week Founder Time
One human reviewing AI output β everything else runs autonomously.
- βΈReview weekly Reddit digest β decide strategic pivots
- βΈApprove content batch before publishing (posts, emails, TikTok scripts)
- βΈReply to 2β3 community DMs flagged as high-priority
- βΈMonthly: review A/B test results, update positioning
GLP-1 Β· Key Risks & Mitigations
Risk Matrix
| Risk | Severity | Mitigation Strategy |
|---|---|---|
| Well-funded incumbent copies injection-cycle feature | HIGH | Data moat: 18mo head start on proprietary food tolerance dataset. By the time they copy, our recommendations are demonstrably superior. |
| GLP-1 market contraction (regulatory, safety concerns) | MED | Oral GLP-1 expansion diversifies. Post-medication maintenance track retains users who stop injecting. |
| Medical liability from nutrition recommendations | MED | RD-reviewed content. FDA "general wellness" safe harbor. Not a medical device β explicitly positioned as wellness. |
| Low retention / high churn after medication stops | HIGH | Build habit infrastructure during medicated window. Community features create exit barriers. Maintenance track by Month 6. |
| User data privacy breach | MED | HIPAA-compatible architecture from Day 1. AES-256 encryption. Consent-gated data tiers. BAA with AWS. |
GLP-1 Β· User Personas
Six Psychological Profiles β Stealth Personalization
Research-grounded archetypes. The app never reveals profiling β users just feel "this app gets me." Onboarding questions that feel like practical setup are psychographic segmentation inputs.
GLP-1 Β· Retention Strategy
How Personas Create Stickiness β The Retention Flywheel
"The persona isn't just a label β it's a contract. The app promises to serve YOUR journey, not a generic GLP-1 user. That promise is why people stay."
β Product Strategy
GLP-1 Β· 90-Day Launch Plan
From Research to Revenue β 10 Weeks
Every channel. Every week. Concrete actions and measurable success thresholds.
Foundation
Infrastructure
Launch Prep
Build Sprint
Launch π
Healthspan100 Β· The Problem
Longevity Science is Trapped in Academic Silos
"The gap between what longevity researchers know and what the public understands is enormous. People are drowning in pseudoscience."
The Problem in Three Parts
Research β Public Gap
Breakthrough studies buried behind paywalls and jargon. Public gets "miracle cures" and wellness grifters instead.
No Visual Authority
Longevity content is text-heavy podcasts and Twitter threads. Zero brands own the visual space.
Trust Deficit
Wellness industry full of unsubstantiated claims. No brand combines science rigor with beautiful execution.
Healthspan100 Β· Market Opportunity
The Longevity Economy Explodes
Why Now?
𧬠Longevity interest explosion
Huberman, Attia, Sinclair drove mainstream awareness. 10x search volume in 3 years.
ποΈ SA's unfair advantage
20yr medical animation library. Strip proprietary IP β AI-generate content at scale.
π± Visual-first social media
Threads get 63% more impressions. Bio-visual content is the unoccupied niche.
π° Creator economy booming
Health creators monetize via courses, sponsorships, communities. Proven playbook.
Healthspan100 Β· Our Solution
The Content Flywheel: SA IP β Viral Longevity Content
A biotech content engine β not a wellness brand. Every post backed by peer-reviewed science.
Animation IP
Adapt
Content
Platforms
Growth
Viral Threads
5β7 tweet threads with contrarian hooks. 37K avg views.
Short-Form Video
SA animation snippets β TikTok/Reels with longevity insights.
Data Visuals
Clinical data as beautiful neon-on-dark infographics.
Newsletter
Weekly longevity digest. Actionable protocols from research.
Brand voice: Precise. Bold. Engineering-minded. "Engineer Your Century." β Cite sources, use correct terminology, distinguish correlation from causation.
Healthspan100 Β· Our Moat
20 Years of Medical Animation IP
Proprietary Advantages
SA Animation Library
Thousands of medical animations built for Pfizer, J&J, Abbott. No one else has this IP to repurpose.
Scientific Credibility
20+ years working with pharma/biotech. Not a lifestyle blogger β a science content company.
AI Content Engine
Steve automates content pipeline: research β script β visual β post. 90% automated.
Competitive Positioning
| Dimension | Us | Huberman | Attia |
|---|---|---|---|
| Visual content | β Core | β Podcast | β Podcast |
| Animation IP | β 20yr | β | β |
| Evidence rigor | β | Mixed | β |
| Scalable via AI | β | β | β |
| Short-form native | β | Clips | β |
Healthspan100 Β· Business Model & Projections
Content β Audience β Monetization
Revenue Streams
Key metric: Audience size β CPM-based revenue scales with followers.
5-Year ARR Projections
π» Bear
Y3 ARR
π Base
Y3 ARR
π Bull
Y3 ARR
Healthspan100 Β· AI Content Factory
AI-Powered Content Factory β Minimal Human Overhead
One human approves. AI agents produce everything else β research, writing, visuals, scheduling, analytics.
- βΈContent approval β review AI-drafted threads & visuals before publish
- βΈStrategy calls β monthly direction: which topics, angles, brand voice shifts
- βΈBrand decisions β sponsorship approvals, partnership vetting
- βΈScience credibility anchor β SA's 20yr track record is the brand's authority
Healthspan100 Β· Key Risks & Mitigations
Risk Matrix
| Risk | Severity | Mitigation Strategy |
|---|---|---|
| Platform algorithm changes reduce organic reach | HIGH | Multi-platform distribution (X, TikTok, YouTube, Instagram, newsletter). Newsletter is owned channel β immune to algorithm shifts. |
| Scientific credibility challenged | MED | Every post cites specific studies (author, year, journal, n=). QC agent verifies. SA's 20yr track record is the credibility signal. |
| Monetization slower than projected | MED | Near-zero operating costs. Content compounds β Year 1 is audience building, revenue follows. Multiple monetization levers diversify risk. |
| AI-generated content quality drift | LOW | Human editorial review (Ashish) on all published content. QC agent catches errors before publish. |
| Competitive longevity creators emerge | MED | SA animation IP is unreplicable. Visual-first differentiation. Podcasters can't easily pivot to our niche. |
ThePrimeYears Β· The Problem
Managing Aging Parents' Medications is a Full-Time Crisis
"Mom takes 7 medications. I have no idea if she's taking them, in the right order, at the right time. I live 800 miles away."
β r/AgingParents caregiver, 2025
The Medication Management Crisis
Complex Regimens
Multiple conditions β multiple drugs β dangerous interactions. Caregivers managing this manually with notes, spreadsheets, and pill organizers.
No Caregiver Visibility
Caregiver has no way to know if doses were taken. No alert when mom skips her blood pressure pill. Discovery happens at the ER.
Existing Apps Fail Elderly
Medisafe, Pill Reminder apps are patient-facing only. No caregiver dashboard. Complex UI not designed for 75+ users. No family coordination layer.
ThePrimeYears Β· Market Opportunity
25M Caregivers Γ Medication Crisis = Urgent, Paying Market
Why Now?
π΄ Silver tsunami accelerating
10,000 Americans turn 65 every day. 25M caregivers managing complex medication regimens with zero digital support.
π Medication management = #1 caregiver pain
$528B/year in medication non-adherence costs (US). No caregiver-facing app exists at scale.
π± Caregiver app market underserved
Existing apps (Medisafe, CareZone) are patient-facing only β no caregiver dashboard, no family coordination, no alerts.
π° Clear willingness to pay
$9.99β14.99/mo caregiver subscription. Peace of mind for loved ones on complex drug regimens. "It's less than two coffees a week."
ThePrimeYears Β· Our Solution
Medication Management App β Core of ThePrimeYears
A caregiver + patient app that solves the #1 pain: medication tracking, missed dose alerts, and drug interaction visibility.
Medication Schedule
Full med list with dose, timing, and interaction flags. Caregiver and patient views synced in real time.
Dose Logging
Patient taps "taken" on their phone. Caregiver sees confirmation. Missed doses trigger instant alerts.
Caregiver Alerts
Push + SMS to caregiver when doses are missed, refills needed, or interactions detected.
Refill Reminders
Auto-calculates supply levels. Alerts caregiver and patient 7 days before runout.
ThePrimeYears Β· Our Moat
Caregiver-First Design + Audience-Led Distribution
Why This Can't Be Copied Easily
Caregiver + Patient Dual View
Only app with real-time caregiver dashboard + simple patient UI. Competitors are single-sided (patient only).
Newsletter-First Distribution
Build audience BEFORE app launch β caregivers trust the brand before they pay. No paid CAC at launch.
"I Built This for My Mom"
Ashish's personal caregiver story is the brand. AARP can't do personal. B2B health companies can't do authentic.
SA Medical Visual IP
Medication explainer visuals powered by 20yr animation expertise. No other caregiver app has this credibility layer.
Competitive Landscape
| Solution | Price | Caregiver View | Med Tracking |
|---|---|---|---|
| Medisafe | Free/$4.99 | β None | β |
| CareZone | Free | Limited | Basic |
| Iamfine (IVR) | $14/mo | Partial | β |
| ThePrimeYears | $9.99β14.99/mo | β Full dashboard | β + Alerts |
ThePrimeYears Β· Business Model & Projections
Med Management App: $9.99β14.99/mo Caregiver Subscription
Revenue Model
Patient-side: FREE (reduces adoption barrier for elderly)
Monthly cost/user: ~$1.50 (hosting + AI) β no per-call cost
Gross margin: ~88%
Break-even: ~60 caregiver subscribers
Revenue Ramp
π» Bear
Y3 ARR
π Base
Y3 ARR
π Bull
Y3 ARR
ThePrimeYears Β· Operations
95%+ Automated β Founder Does the Irreplaceable 5%
Founder owns relationships and strategy. AI agents handle everything operational.
- βΈContent strategy β newsletter angle, medication topic calendar, brand voice
- βΈCaregiver community relationships β key Facebook groups, elder law partnerships
- βΈMedical advisor partnerships β geriatric pharmacist advisors, RN review board
- βΈApprove newsletter before each send β medical accuracy check
ThePrimeYears Β· Key Risks & Mitigations
Risk Matrix
| Risk | Severity | Mitigation Strategy |
|---|---|---|
| Elderly patients resistant to logging doses (app adoption) | HIGH | Ultra-simple patient UI: single large button per medication. Caregiver can log on behalf. SMS/call reminder fallback. Beta test with 10 families, iterate before launch. |
| Medical liability β app seen as clinical guidance | HIGH | Explicit disclaimers: tracking tool, not medical advice. "General wellness" safe harbor. No drug interaction alerts without pharmacist review. RN advisory board from day one. |
| Medisafe / large health systems copy caregiver dashboard | MED | Newsletter-first audience creates trust moat before app launch. "I built this for my mom" brand can't be replicated by institutional players. SA visual explainers differentiate. |
| Data privacy breach β medication data is sensitive | MED | HIPAA-compatible architecture. AES-256 encryption. Consent-gated sharing. No medication data sold to pharma (trust is the brand). AWS BAA from day one. |
| Distribution β reaching caregivers without paid ads | LOW | Newsletter builds audience before app launch. Facebook caregiver communities (8M+ members). B2B channel: elder law firms, credit unions, senior centers. TiE network. |
Portfolio Summary
Three Markets. One Operator. AI-First.
All three ventures share a common DNA: AI-powered operations, content-first go-to-market, minimal human overhead, and Ashish's 20-year medical science credibility.
ashishckhera@gmail.com Β· scientificanimations.com
Head-to-Head Β· All Three Ventures
At a Glance
| Dimension | π GLP-1 Meal Planner | 𧬠Healthspan100 | π ThePrimeYears |
|---|---|---|---|
| Category | Consumer App | Media Brand | Medication Management App |
| Build Status | Research Complete Β· Building | Brand Defined | MVP Built β |
| Market Size (TAM) | $66.6B | $27B | 25M caregivers |
| Addressable (SAM) | $1.44B | $2B | 3M tech-savvy |
| Pricing | $14.99/mo subscription | Free + affiliate/sponsors | $9.99β14.99/mo caregiver Β· Free patient |
| Core Moat | Injection-cycle Γ meal outcome dataset | SA's 20yr medical animation IP | Caregiver-first dual dashboard + newsletter audience |
| AI Role | Meal gen, coaching, personalization | Content factory, trend analysis | Med dose logging, missed-dose alerts, newsletter drafting |
| Y3 Base ARR | $1.2M | $400K | $360K |
Market Opportunity Β· Comparative View
Three Big Markets, One Team
21.5% nausea rate Β· Muscle loss crisis
37K avg thread views on day one
$7,242 avg caregiver cost/year
5-Year Revenue Β· Bear / Base / Bull
Financial Comparison
Execution Strategy Β· Where to Start
Recommended Sequencing
| Venture | Risk | Revenue | Speed |
|---|---|---|---|
| π‘οΈ ThePrimeYears | Low | Med | Fast |
| 𧬠H100 | Low | LowβMed | Immediate |
| π GLP-1 | Med | High | Slower |